Abstract P-023

P 023

Ageing is associated with a shift in normal patterns of DNA methyla-tion, including increased methylation of CpG islands. This may have significant effects on gene expression and could, in part, underlie the strong association between ageing and human disease. To study the extent and variability of age-associated methylation, we have studied peripheral blood leukocyte (PBL) DNA samples from 490...

023 Mw4355

Sir, The recent article by Gosden et al. prompted me to reflect on the widespread use of disc diffusion methods for determining antibiotic susceptibility that ignore an important finding of the definitive studies of Cooper and Linton on the formation of inhibition zones. These investigators showed that, although the intrinsic susceptibility of a bacterial isolate, under the in-vitro conditions ...

PW02-023 - Qualitative aspects of autoinflammatory diseases

Introduction In pediatric rheumatology, the lack of scales showing activities of illness in the patients groups, the absence of biomarkers for the severity of damage led the scientific world to develop a scale where the patient can make an self-assessment with quantitative results. So, a necessity has been occurred to develop a multidimensional scale which is understandable, applicable and comp...

P03-023 – Autoinflammatory diseases database in Japan

Introduction In recent years, responsible genes for autoinflammatory diseases have been increasingly known and clinical phenotype-genotype correlations of these diseases have been explored through international clinical databases such as EUROFEVER project. However, clinical features of genetic disorders could be affected by countries and races of the patients. Actually, patients with Familial M...

abstract