Abstract #1403921: Characteristics of Children and Adolescents with Hashimoto’s Thyroiditis in a Multiethnic Community Hospital

Hashimoto's thyroiditis (HT), an autoimmune thyroid disorder, is the most common cause of acquired hypothyroidism in children and adolescents. HT familial with female predominance. It has peak incidence school-aged Whites Asians those other conditions. In addition to goiter, poor linear growth disruption pubertal development are common. The diagnosis made by presence autoantibodies (Abs) can be confirmed heterogeneous echogenicity on sonogram. There increased risk for papillary carcinoma (PTC) HT. aim this study was explore characteristics pediatric patients a multiethnic community hospital where majority Hispanic Asian. A retrospective review conducted. Patients 0-21 years seen Pediatric Endocrine Clinic at Flushing Hospital Medical Center between 2013 2021were included. Data extracted from EHR included demographics, clinical findings, comorbidities, function tests, autoantibodies, sonogram fine needle aspiration (FNA) results treatment. sample characterized using descriptive statistics. Of 114 identified HT, 80 (70%) were female. mean age time 12.6+4.2 years. 66 documented ethnicity, 59% Hispanic. Family history dysfunction present 35%. presenting complaint goiter (47%). Elevated thyrotropin 86%. Comorbidities diabetes (5%), celiac disease (2%) vitiligo (2%). Both anti-thyroglobulin antibodies (anti-Tg Abs) anti-peroxidase (anti-TPO) Abs 60%, anti-TPO only 22% anti-Tg 9%. All had sonogram: 64% revealed echogenicity, 4% homogeneous 32% normal. nodules cysts reported 12%, 24%, No patient met criteria FNA. overt or nodules/cysts prescribed levothyroxine. Our mostly underrepresented population previous studies. Female male ratio almost 4:1 12.6 years, concurring known epidemiology. Hypothyroidism Having both more than having one Abs. Thyroid confirmatory two-thirds. Nodules but did not lead Future research exploring associations PTC will require extended follow up.