Abrogation of protein phosphatase 6 promotes skin carcinogenesis induced by DMBA

Modulation of DMBA- induced biochemical and histopathological changes by Syzygium cumini seed extract during skin carcinogenesis

Effect of Bauhinia Variegate Bark Extract on DMBA-Induced Mouse Skin Carcinogenesis: A Preliminary Study

Bauhinia variegata Linn. (Kanchnar/Rakta kanchan), is a widely used medicinal plant by the tribals throughout India and popular in various indigenous system of medicine like Ayurveda, Unani and Homoeopathy. In the present investigations, the anticarcinogenic activity of Bauhinia variegate bark extract was evaluated using two stage protocol in skin papillioma model in Swiss albino mice. The sign...

Chemomodulatory Potential of Flaxseed Oil Against DMBA/Croton Oil–Induced Skin Carcinogenesis in Mice

The present study was conducted to evaluate the potential of flaxseed oil to prevent chemically induced skin cancer in mice. Cancer was induced on 2-stage skin carcinogenesis model by single topical application of 7,12 dimethylbenz [a]anthracene (DMBA), as, initiator, and two weeks later it was promoted by croton oil treatment thrice a week on the dorsal surface of mice for 16 weeks. Flaxseed o...

Chemopreventive activity of methanol extract of Melastoma malabathricum leaves in DMBA-induced mouse skin carcinogenesis

Background: Melastoma malabathricum L. Smith (family Melastomaceae) is a shrub that has been used by the Malay practitioners of traditional medicine to treat various types of ailments. The present study aimed to determine the chemopreventive activity of methanol extract of M. malabathricum leaves (MEMM) using the standard 7,12dimethylbenz(α)anthracene (DMBA)/croton oil-induced mouse skin carcin...

Chemopreventive activity of methanol extract of Melastoma malabathricum leaves in DMBA-induced mouse skin carcinogenesis.

BACKGROUND Melastoma malabathricum L. Smith (family Melastomaceae) is a shrub that has been used by the Malay practitioners of traditional medicine to treat various types of ailments. The present study aimed to determine the chemopreventive activity of methanol extract of M. malabathricum leaves (MEMM) using the standard 7,12-dimethylbenz(α)anthracene (DMBA)/croton oil-induced mouse skin carcin...