Abolishment of fear memory-disruptive effects REM sleep deprivation by harmane
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چکیده
منابع مشابه
REM sleep deprivation and conditioned fear in rats
As a test of the hypothesis that REM sleep deprivation reduces fear, the freezing behavior of 60 rats was measured under the conditions of the Bolles-Collier (1976) paradigm. These animals were first exposed to one of three treatments for 4 day s: a dry-environment control, a wetenvironment control, or a 4-day REM deprivation period. Next, the animals were fear conditioned in a square-box and t...
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Introduction: There are several evidences that show various environmental stresses during pregnancy, affect physiological behavior of the offspring. In this study the effects of REM (Rapid Eye Movement) sleep deprivation of pregnant rats on spatial learning of adult male offspring by Morris water maze were investigated. Methods: Water tank technique was used for inducing REM sleep deprivatio...
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background and objective: Hypocretins (orexins) are recently discovered neuropeptides that are produced in a very restricted area of the lateral hypothalamus. These peptides were originally associated with feeding behavior, but have come to be viewed as essential in causing narcolepsy and regulating sleep. Narcolepsy is a sleep disorder associated with REM sleep abnormalities, and it is likely ...
متن کاملSleep Deprivation Impairs Consolidation of Cued Fear Memory in Rats
Post-learning sleep facilitates negative memory consolidation and also helps preserve it over several years. It is believed, therefore, that sleep deprivation may help prevent consolidation of fearful memory. Its effect, however, on consolidation of negative/frightening memories is not known. Cued fear-conditioning (CuFC) is a widely used model to understand the neural basis of negative memory ...
متن کاملSleep deprivation selectively impairs memory consolidation for contextual fear conditioning.
Many behavioral and electrophysiological studies in animals and humans have suggested that sleep and circadian rhythms influence memory consolidation. In rodents, hippocampus-dependent memory may be particularly sensitive to sleep deprivation after training, as spatial memory in the Morris water maze is impaired by rapid eye movement sleep deprivation following training. Spatial learning in the...
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ژورنال
عنوان ژورنال: Biomedicine & Pharmacotherapy
سال: 2019
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2018.10.179