Abnormal cardiac pain perception in syndrome X

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Abnormal cardiac pain perception in syndrome X.

OBJECTIVES The purpose of this study was to determine whether a diminished cardiac pain threshold contributes to chest pain in patients with syndrome X. BACKGROUND There have been some reports of an altered pain perception in syndrome X. METHODS Intracardiac catheter manipulation was performed in four groups of patients (syndrome X [group 1, 36 patients]; mitral valve disease and normal cor...

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Spinal cord stimulation normalizes abnormal cortical pain processing in patients with cardiac syndrome X.

Cardiac syndrome X (CSX) is characterized by effort angina, ST-segment depression during stress tests and normal coronary arteries. Abnormal nociception was suggested in these patients by studies showing a reduced cardiac pain threshold; furthermore, we recently found a lack of habituation to pain stimuli using recording of laser evoked potentials (LEPs). In CSX patients with severe angina, spi...

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Metoprolol improves endothelial function in patients with cardiac syndrome X

Endothelial dysfunction which is manifested by the loss of nitric oxide bioavailability, is an increasingly recognized cause of cardiac syndrome X (CSX) and beta blockers are used for the treatment of this syndrome. Thus, the aim of this study was to investigate effects of metoprolol, as a beta blocker, on endothelial function in CSX patients. The study included 25 CSX patients (20 female/ 5 ma...

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Metoprolol improves endothelial function in patients with cardiac syndrome X

Endothelial dysfunction which is manifested by the loss of nitric oxide bioavailability, is an increasingly recognized cause of cardiac syndrome X (CSX) and beta blockers are used for the treatment of this syndrome. Thus, the aim of this study was to investigate effects of metoprolol, as a beta blocker, on endothelial function in CSX patients. The study included 25 CSX patients (20 female/ 5 ma...

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Central neural contribution to the perception of chest pain in cardiac syndrome X.

OBJECTIVE To investigate the central neural contribution to chest pain perception in cardiac syndrome X (angina-like pain, ECG changes during stress, angiographically normal coronary arteriogram). SUBJECTS Eight syndrome X patients and eight healthy volunteers. METHODS Dobutamine stress using echocardiography to assess myocardial function, and positron emission tomography to measure changes...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 1994

ISSN: 0735-1097

DOI: 10.1016/0735-1097(94)90284-4