Aberrant Cementum Phenotype Associated With the HypophosphatemicHypMouse
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چکیده
منابع مشابه
Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype.
Aberrant methylation of 5' CpG islands is thought to play an important role in the inactivation of tumor suppressor genes in cancer. In colorectal cancer, a group of tumors is characterized by a hypermethylator phenotype termed CpG island methylator phenotype (CIMP), which includes methylation of such genes as p16 and hMLH1. To study whether CIMP is present in gastric cancer, the methylation st...
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Aberrant methylation of 5* CpG islands is thought to play an important role in the inactivation of tumor suppressor genes in cancer. In colorectal cancer, a group of tumors is characterized by a hypermethylator phenotype termed CpG island methylator phenotype (CIMP), which includes methylation of such genes as p16 and hMLH1. To study whether CIMP is present in gastric cancer, the methylation st...
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Genetic abnormalities of cholangiocarcinoma have been widely studied; however, epigenomic changes related to cholangiocarcinogenesis have been less well characterized. We have profiled the DNA methylomes of 28 primary cholangiocarcinoma and six matched adjacent normal tissues using Infinium's HumanMethylation27 BeadChips with the aim of identifying gene sets aberrantly and epigenetically regula...
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Inactivation of methylcytosine dioxygenase, ten-eleven translocation (TET) is known to be associated with aberrant DNA methylation in cancers. Tumors with a CpG island methylator phenotype (CIMP), a distinct subgroup with extensive DNA methylation, show characteristic features in the case of colorectal cancer. The relationship between TET inactivation and CIMP in colorectal cancers is not well ...
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DNA copy number alterations are a hallmark of cancer. Understanding their role in tumor progression can help improve diagnosis, prognosis and therapy selection for cancer patients and can contribute to the development of personalised therapies. High-resolution, genome-wide measurements of DNA copy number changes for large cohorts of tumors are currently available, owing to the rapid development...
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ژورنال
عنوان ژورنال: Journal of Periodontology
سال: 2009
ISSN: 0022-3492,1943-3670
DOI: 10.1902/jop.2009.090129