ABCG5/8 variants are associated with susceptibility to coronary heart disease

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منابع مشابه

ABCG5/8 variants are associated with susceptibility to coronary heart disease.

ATP-binding cassette sub-family G member 5 (ABCG5) and ABCG8 are members of an ATP-binding cassette transporter superfamily. ABCG5 and ABCG8 variants affected serum levels of cholesterol and were considered as risk factors for coronary heart disease (CHD). The present control study analyzed ABCG5 and ABCG8 variants in a population for association with the risk of CHD. A total of 417 CHD patient...

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Is Subclinical Thyroid Dysfunction Associated With with Coronary Heart Disease?

Introduction: Previous cohort studies reported contradictory data on the association between subclinical thyroid dysfunction and coronary heart disease (CHD). Regarding this, the present study was conducted to illuminate this relationship. Materials and Methods: For the purpose of the study, 3,066 participants employed in a study conducted by Azizi et al. aged ≥ 20 years were subjected to thyro...

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Association between Long Noncoding RNA ANRIL Expression Variants and Susceptibility to Coronary Artery Disease

Animal cells possess thousands of long non-coding (lnc) RNAs, such as antisense noncoding RNA in the INK4 locus (ANRIL) , which have regulatory roles in the cells’ molecular mechanisms, including X-chromosome inactivation, and developmental processes.  These lnc RNAs are known to influence the extensive spectrum of age-related disorders. Accordingly, there is evidence for the role of...

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Variants in the SMARCA4 gene was associated with coronary heart disease susceptibility in Chinese han population

BACKGROUND Coronary heart disease (CHD) is the leading cause of death worldwide. Many single-nucleotide polymorphisms (SNPs) are found to be related to the risk of CHD in previous studies. This study investigated whether polymorphism of SMARCA4 gene is associated with CHD. MATERIALS AND METHODS Genotypes at five CHD-relevant SNPs were determined in 456 cases of incident CHD and 685 unaffected...

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Antibodies to periodontal pathogens are associated with coronary heart disease.

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ژورنال

عنوان ژورنال: Molecular Medicine Reports

سال: 2014

ISSN: 1791-2997,1791-3004

DOI: 10.3892/mmr.2014.2098