AB1370 DEMOGRAPHICAL, SOCIOPROFESSIONAL FACTORS AND HABITS ASSOCIATED WITH CHRONIC WIDESPREAD PAIN IN A LARGE GENERAL POPULATION COHORT

Background Clinical and demographic characteristics associated with chronic widespread pain (CWP) are well known, contrary to the social professional in general population. Objectives To evaluate set of CWP. Methods The Constances cohort consisting randomly selected volunteers aged 18 69 years, between 2013 2020 France (ref). An ancillary study from this aims identify musculoskeletal using Nordic Questionnaire. Chronic was defined as at least 4 6 areas, during 30 days previous year. Individuals diagnosed a cancer were excluded. Demographic, clinical, social, occupational data inclusion collected. Missing imputed. Multivariate analysis performed. Results 193,436 people included, whom 7% (13,447 people) suffered Female gender, age, higher BMI, depression, medium or high physical activity work, current past smoking, less sleep duration, low socioprofessional category Diploma protective factor, leisure activity, while job search, household income, alcohol cannabis not poorly Table 1. Odds Ratio - Confidence interval 95% sex 1.91 [1.82 1.99] Age (reference 18-30 years) 40 years: 1.55 [1.40 1.72] 50 2.35 [2.13 2..60] 60 3.40 [3.07 3,76] 2,92 [2.60 3.29 BMI 18.5 25) < 18.5: 0.83 [0.73 0.95] 25 29.9: 1.19 [1.14 1.24] 34.9: 1.40 [1.32 1.49] 35 39.9: 1.48 [1.34 1.63] Depression (CESD score) 2.19 [2.10 2.28] Sleep duration (Odds ratio for one hour) 0.92 [0.91 0.93] Alcohol (reference: no misuse dependance Audit Score) Misuse 0.93 [0.89 0.97] Dependance 1.04 [0.95 1.13] Smoking smoking) Previous smoking: 1.30 [1.24 1.36] Actual 1.25 [1.18 1.32] Cannabis never use) used more than year ago 0.96 1.01] Used 12 last months 0.99 [0.87 1.11] 1.16 [1.04 1.28] Physical activity) Very activity: [0.85 1.09] 1.01 moderately 0.90 [0.81 Activity [0.83 1.03] Quite 0.80 [0.71 0.89] Important 0.84 [0.75 work sedentary) slightly active (walking/ handling 10 kg): 1.09 [1.03 1.16] (handling objects kg) 1.58 [1.47 1.70] highly (heavy > 2.39 [2.19 2.62] Socio-professional intermediate profession) Farmer 1.23 [0.72 2.01] Craftsman, merchant business owner 1.08 [0.94 1.23] Executive intellectual profession 1.00] Employee [1.02 1.14] Worker 1.21 [1.12 1.30] Never 0.88 1.08] [0.93 without diploma) certificate secondary education 0.98 [0.88 Certificate competence High school diploma [0.80 2 years after 0.76 [0.68 0.84] Bachelor’s degree 0.65 [0.57 0.73] Master’s 0.58 [0.51 0.65] Professional situation employed) In formation 0.79 [0.66 Job seeker Without [0.78 1.04] No due medical disease 2.46 [2.16 2.80] Pensioner 0.94 0.91 1.02] Household income 1000 1500 euros) Less 45 euros: 0.89 [0.69 1.12] 450 euros 2100 2800 1.05 [0.97 4200 1.02 1.10] More [0.82 Cannot answer Do want Conclusion CWP remains frequent French population is significantly specific socioeconomic factors. Reference [1]Zins M et al. 2015 Eur J Epidemiol Acknowledgements: NIL. Disclosure Interests None Declared.