AB0887-HPR CHARLSON COMORBIDITY INDEX (CCI) IN RHEUMATOID ARTHRITIS: CLASSIFICATION AND CORRELATIONS
نویسندگان
چکیده
Background: Charlson Comorbidity Index[1] is a tool including age and chronic diseases assessing the comorbidity burden. The burden in RA patients determine morbidity mortality. Objectives: To assess classification of CCI with usage health-care system (outpatient clinics) real-world setting. Methods: 327 from large outpatient service central hospital were retrospectively reviewed. Demographic characteristics, treatment for comorbidities recorded. Index (CCI) was measured classified as low, intermediate high score 1-2, 3-4 >=5 points, respectively. Its correlation polypharmacy necessity biologic DMARDs studied. Univariable multivariable analyses performed. Results: Data (75,8% females, 24,2%males) mean±SD 63±11,8 years disease duration 113±63 months, 3±1,2 points (mean±SD) maximum observed at 7 points. High (>=5points) 9,2% majority (3-4points) 55%. All fulfilled criteria polypharmacy. Patients had 9,7 times more probability than low (p=0.09, 1.4-2.5 95%CI). 70 treated biologic-DMARDs (21,7%), TNFa inhibitors (16,5%). In receiving or CCI. Τhe most likely explanation severity that predominated, its complications possible overlap other conditions. Conclusion: score-meaning comorbidities- completely. characterized less comorbidities. References: [1]Charlson E M et al. A new method classifying prognostic longitudinal studies:development validation. J Chronic Dis. 1987;40(5):373-83. Disclosure Interests: None declared
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2021
ISSN: ['1468-2060', '0003-4967']
DOI: https://doi.org/10.1136/annrheumdis-2021-eular.1103