AB042. Oxidative stress and male infertility

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Oxidative stress & male infertility.

The male factor is considered a major contributory factor to infertility. Apart from the conventional causes for male infertility such as varicocoele, cryptorchidism, infections, obstructive lesions, cystic fibrosis, trauma, and tumours, a new and important cause has been identified: oxidative stress. Oxidative stress is a result of the imbalance between reactive oxygen species (ROS) and antiox...

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A Review: Role of oxidative stress in male infertility

Recent studies have shown that reactive oxygen species (ROS) have a very important role in the intracellular signaling process in physiological conditions. On the other hand, during the recent decade it has been indicated that ROS play a role in various types of male infertility and it is due to the overproduction of ROS or decrease in the antioxidant defense system in the reproductive system a...

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Oxidative stress and sperm chromatin damage in male infertility.

Researchers studying the causes of male infertility have recently focused on the role played by reactive oxygen species (ROS)—a highly reactive oxidizing agent belonging to the class of free radicals. ROS are produced by a variety of semen components, and antioxidants in the seminal fluid keep their levels in check. Small amounts of ROS help spermatozoa acquire their necessary fertilizing capab...

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Relationship amongst teratozoospermia, seminal oxidative stress and male infertility

BACKGROUND Spermatozoa morphology is an important and complex characteristic of the fertilization capacity of male germ cells. Morphological abnormalities have been observed to be accompanied by reactive oxygen species (ROS) overproduction and further damage to spermatozoa, ultimately leading to infertility. Therefore, this study aimed to examine the relationship between seminal ROS production ...

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Oxidative stress and antioxidants in male infertility: a difficult balance

Infertility is one of the most stressful conditions amongst married couples. Male factor infertility is implicated in almost half of these cases. Recent advances in the field of reproductive medicine have focused the attention of many researchers to consider reactive oxygen species (ROS) as one of the mediators of infertility causing sperm dysfunction. Although, ROS is involved in many physiolo...

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ژورنال

عنوان ژورنال: Translational Andrology and Urology

سال: 2018

ISSN: 2223-4683,2223-4691

DOI: 10.21037/tau.2018.ab042