A4 Synergistic vascular effects of dietary sodium supplementation and angiotensin II administration
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چکیده
منابع مشابه
Structural vascular changes in hypertension: role of angiotensin II, dietary sodium supplementation, blood pressure, and time.
The dose and time dependence of angiotensin II (Ang II) induced hypertension and structural vascular changes and the effect of dietary sodium supplementation on these relationships were investigated. Male Sprague-Dawley rats were treated with 50, 100, or 200 ng . kg-1 . min-1 Ang II subcutaneously for 4 or 12 weeks on normal sodium diet (0.7% NaCl) or with 50 ng . kg-1 . min-1 Ang II SC for 12 ...
متن کاملStructural vascular changes in hypertension: role of angiotensin II, dietary sodium supplementation, and sympathetic stimulation, alone and in combination in rats.
Elevated circulating angiotensin (Ang) II levels, dietary sodium, and sympathetic stimulation are recurrent themes of hypertension research, but their in vivo interaction in physiologically meaningful doses has not been adequately investigated. In this study, the interaction of a subpressor dose of Ang II (50 ng. kg(-1). min(-1) SC), 2% NaCl diet, and sympathetic stimulation in the form of over...
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The present research was aimed to study the effects of different sources of carotenoids and their varying concentrations on the reproductive functions of goldfish. The study was carried out in seven treatments with three replicates at the Bony Fish Hatchery Complex (Rasht, Iran) from December 2011 to May 2012. Experimental diets containing 50, 100, and 150 mg kg-1 astaxanthin and 50, 100, and 1...
متن کاملVascular angiotensin II receptors and sodium balance in rats. Role of kidneys and vascular renin activity.
The relationship between the vascular response. to angiotensin II and sodium balance was studied by measuring the volume of specific antiserum needed to block the pressor response to a standard dose of angiotensin II in rats. In normal rats, sodium depletion reduced the volume of antiserum required to prevent a pressor response to 50 ng of angiotensin II from 0.32 to 0.22 ml; sodium loading inc...
متن کاملHuR mediates the synergistic effects of angiotensin II and IL-1β on vascular COX-2 expression and cell migration.
BACKGROUND AND PURPOSE Angiotensin II (AngII) and IL-1β are involved in cardiovascular diseases through the induction of inflammatory pathways. HuR is an adenylate- and uridylate-rich element (ARE)-binding protein involved in the mRNA stabilization of many genes. This study investigated the contribution of HuR to the increased expression of COX-2 induced by AngII and IL-1β and its consequences ...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 1997
ISSN: 0895-7061
DOI: 10.1016/s0895-7061(97)89217-5