A1 milk and beta-casomorphin-7

Milk is composed of water, proteins, lipids, lactose, vit-amins, and minerals. More than 80% most mam-mals’ milk proteins are con-stituted by caseins. Casein a group they sub-divided into αs1-, αs2-, β- -casein families. Among these ca-sein families, -casein the second abundant pro-tein. Different mutations in cow gene led to 12 genetic variants common A1 A2. The A2 differ only at amino acid position 67, which histi-dine or proline milk. This difference sequence sug-gests conformational change secondary structure expressed β-casein. that contains β-casein known as milk, respectively. releases an bioactive pep-tide called beta-casomorphin-7 (CM-7) small intestine. Beta-casomorphin-7 released from respon-sible for many human dis-orders like type-1 diabetes, autism, schizophrenia, alz-heimer’s disease (AD), at-tention deficit hyperactivity disorder (ADHD), multiple sclerosis (MS) heart diseases.