A Xenograft Model of Vestibular Schwannoma and Hearing Loss
نویسندگان
چکیده
منابع مشابه
Vestibular schwannoma presenting as sudden hearing loss Summary
The Sudden Hearing Loss (SHL) is a symptom caused by more than 60 different diseases, including Vestibular Schwannoma (VS). Shaia & Sheehy (1976) presented a study with 1,220 cases of SHL reporting 1% incidence of VS. There is no specific characteristic for the diagnosis of VS and Magnetic Resonance Imaging (MRI) is the gold standard exam to diagnose such disease. Aim: To determine the real inc...
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OBJECTIVE The aim of the present study was to evaluate the long-term hearing during "wait and scan" management of vestibular schwannomas. SUBJECTS During a 33-year period, from 1976 to 2008, 1,144 patients with vestibular schwannoma were allocated to observation by the wait and scan policy, with annual magnetic resonance imaging and audiologic examination. Two complete pure-tone and speech di...
متن کاملHearing preservation in 2.7 cm vestibular schwannoma.
Hearing preservation is exceedingly difficult in vestibular schwannoma surgery, especially with increasing tumor size. We herein report a case of hearing preservation in a 2.7 cm vestibular schwannoma, where the patient maintained her pre-operative hearing threshold of 55 dB till a year after surgery. Hence, it appears that an attempt at hearing preservation is worth pursuing.
متن کاملDevelopment of a vestibular schwannoma xenograft zebrafish model for in vivo antitumor drug screening.
OBJECTIVES/HYPOTHESIS The development of a simple, reliable, and cost-effective animal model greatly facilitates disease treatment. We aimed to establish a rapid, simple, and reproducible live zebrafish vestibular schwannoma xenograft model for antitumor drug screening. METHODS We optimized each of the following conditions for tumor cell xenografts in zebrafish larvae: larval stage, incubatio...
متن کاملNormal hearing after resection of a large vestibular schwannoma.
Dr. Marcelo D. Vilela – Department of Neurological Surgery / Harborview Medical Center 325 9 Avenue Seattle WA 98104 USA Box 359766. E-mail: [email protected] Advances in anesthesia and surgical techniques have brought the surgical mortality rate for vestibular schwannomas (VS) to less than 1%. Increased preservation rates of facial and cochlear function were observed in the most recent...
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ژورنال
عنوان ژورنال: Otology & Neurotology
سال: 2018
ISSN: 1531-7129,1537-4505
DOI: 10.1097/mao.0000000000001766