منابع مشابه
A Unified Theory of Gene Expression
The human genome has been called "the blueprint for life." This master plan is realized through the process of gene expression. Recent progress has revealed that many of the steps in the pathway from gene sequence to active protein are connected, suggesting a unified theory of gene expression.
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with other components of the transcription machinery, Cheshire SK10 4TJ promote access to DNA and facilitate the recruitment United Kingdom of the RNA polymerase enzymes to the transcriptional 2 Howard Hughes Medical Institute start site. Three RNA polymerases function in eukaryDivision of Nucleic Acids Enzymology otes (RNAP I, II, and III). Transcription of protein-coding Department of Biochem...
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In this paper, a unified beam theory is developed and applied to study the buckling response of two types of functionally graded sandwich beams. In the first type (Type A), the sandwich beam has a hardcore whereas in the second type (Type B), the sandwich beam has a softcore. In both the type of beams, face sheets are made up of functionally graded material. The material properties of face shee...
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A summary of papers on a set of theories which show an alternative path for the development of theoretical physics from 1905 resulting in a unified theory of electricity, magnetism, gravity, and inertia. It explores the route open to Lorentz, had he know of the Rutherford atom and the three quark model of nucleons, before Einstein published his theory of relativity. It is possible that with onl...
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We investigate a model of optimal regulation, intended to describe large-scale differential gene expression. Relations between the optimal expression patterns and the function of genes are deduced from an optimality principle: the regulators have to maximise a fitness function which they influence directly via a cost term, and indirectly via their control on important cell variables, such as me...
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ژورنال
عنوان ژورنال: Cell
سال: 2002
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(02)00655-4