A Tool for Automatic Correction of Endogenous Concentrations: Application to BHB Analysis by LC–MS-MS and GC-MS

Chemical Analysis of Pesticides Using GC/MS, GC/MS/MS, and LC/MS/MS

There are well over 500 registered pesticides worldwide for use in agricultural regions and new agrochemicals are introduced to the marketplace continuously. This chapter deals with the chemical analysis methods for the main pesticide chemical classes that are most frequently analyzed with gas chromatography (GC) or liquid chromatography (LC) coupled to mass spectrometry (MS). GC amenable pesti...

High through put analysis of MALDI time-of-flight MS/MS and LCMS/MS data

Stereochemical Analysis of Monodeuterated Isomers By GC/MS/MS

GC/MS/MS techniques to quantitate mixtures of acyclic stereoisomers are explored for a set of secondary n-alkyl phenyl ethers vicinally substituted with deuterium. Examination of a set of test compounds using a commercial quadrupole ion trap instrument (GC/QIT) reveals large differences between threo and erythro diastereomers when trapped molecular ions expel neutral alkene as a result of colli...

Phytochemical analysis of Cyperus rotundus hexane fraction by GC-MS and total oligomeric flavonoid fraction by 4D GCXGC TOF-MS

Cyperus rotundus (CR) is a traditional medicinal herb, and recent studies demonstrated its pharmacological effects to cure neurological disorders. In our earlier reports, we also found that CR exerts anxiolytic effects and improves memory impairment in hypoxia-induced rats. In vitro CR also effectively ameliorates oxidative stress-induced SH-SY5Y neuronal cell damage. In the present study, we e...

Selective and comprehensive analysis of organohalogen compounds by GC × GC–HRTofMS and MS/MS

Thousands of organohalogen compounds, including hazardous chemicals such as polychlorinated biphenyls (PCBs) and other persistent organic pollutants (POPs), were selectively and simultaneously detected and identified with simple, or no, purification from environmental sample extracts by using several advanced methods. The methods used were software extraction from two-dimensional gas chromatogr...