A theory that's hard to digest

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چکیده

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15 صفحه اول

Noisy Data Make the Partial Digest Problem NP-hard

The problem to find the coordinates of n points on a line such that the pairwise distances of the points form a given multi-set of n 2 distances is known as Partial Digest problem, which occurs for instance in DNA physical mapping and de novo sequencing of proteins. Although Partial Digest was – as a combinatorial problem – already proposed in the 1930’s, its computational complexity is still u...

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ژورنال

عنوان ژورنال: Nature

سال: 1999

ISSN: 0028-0836,1476-4687

DOI: 10.1038/21364