A THEORETICAL ANALYSIS OF THE EFFECTS OF SEX CHROMOSOME ANEUPLOIDY ON X AND Y CHROMOSOME MEIOTIC DRIVE

Sex Chromosome Meiotic Drive

Rapid evolution of a Y-chromosome heterochromatin protein underlies sex chromosome meiotic drive.

Sex chromosome meiotic drive, the non-Mendelian transmission of sex chromosomes, is the expression of an intragenomic conflict that can have extreme evolutionary consequences. However, the molecular bases of such conflicts remain poorly understood. Here, we show that a young and rapidly evolving X-linked heterochromatin protein 1 (HP1) gene, HP1D2, plays a key role in the classical Paris sex-ra...

Meiotic drive and sex chromosome cycling.

Sex-linked meiotic drive is found in a broad variety of taxa, including insects, birds, and mammals. In populations of some species, we see four types of sex chromosomes segregating: normal and driving X chromosomes and susceptible and resistant Y chromosomes. A theoretical analysis shows that a stable four-chromosome equilibria is a more common outcome in these systems than previously recogniz...

Suppression of Sex-ratio Meiotic Drive and the Maintenance of Y-chromosome Polymorphism in Drosophila.

Like several other species of Drosophila, D. quinaria is polymorphic for X-chromosome meiotic drive; matings involving males that carry a "sex-ratio" X chromosome (XSR ) result in the production of strongly female-biased offspring sex ratios (Jaenike 1996). A survey of isofemale lines of D. quinaria from several populations reveals that there is genetic variation for partial suppression of this...

Sex-ratio meiotic drive in Drosophila simulans is related to equational nondisjunction of the Y chromosome.

The sex-ratio trait, an example of naturally occurring X-linked meiotic drive, has been reported in a dozen Drosophila species. Males carrying a sex-ratio X chromosome produce an excess of female offspring caused by a deficiency of Y-bearing sperm. In Drosophila simulans, such males produce approximately 70-90% female offspring, and 15-30% of the male offspring are sterile. Here, we investigate...