A Technique of Deep Brain Stimulation of the Globus Pallidus Interna for Dystonia Under General Anesthesia With Sevoflurane

Background Globus pallidus interna (GPi) deep brain stimulation (DBS) is an established surgical procedure that confers a benefit in medication refractory dystonia. Patients with generalized dystonia require general anesthesia (GA) for the surgery as their movements may hinder procedure. General anesthetics tend to dampen microelectrode recordings (MERs) from GPi. Methods We describe our experience series of consecutive patients who underwent bilateral GPi DBS using standard and MER under GA sevoflurane maintenance anesthetic drug. All had Medtronic 3,387 leads implanted connected RC battery. sequential programming after surgery. Results The mean age 13 was 46.5 years range 29 71 years. Every patient case received various doses (1.37% 2.11%) inhaled maintenance. Sevoflurane provided adequate allowed accurate MERs No adverse effects were encountered. On follow-up programming, significant improvements attesting accuracy electrode placements. Conclusions report main benefits identified have been reduction dystonia-related allow performance signals not suppressed by sevoflurane. This mapping placement implants