A Systematic Review Of Metallic Nanoparticles: Synthesis, Biological Activities & Applications

Metallic nanoparticles (MNP) have captivated scientist for over a century and are now profoundly utilized in biomedical sciences engineering. MNPs interact with key cellular organelles biomolecules, including DNA, enzymes, ribosomes, liposomes, which can an impact on gene expression, oxidative stress, protein enzyme activation, cell membrane permeability. It has been shown that the metabolites of living organisms like bacteria, yeast, fungi, plant cells convert inorganic metal ions into NPs. By utilizing biological agents green chemistry, metallic produced less adverse effects more effective against cancer cells. These physically infiltrate kill them by activating variety biochemical pathways, apoptosis, necrosis, autophagy. This review focuses (copper, gold, silver) their usefulness treating endemic diseases cancer, hepatitis, malaria. In near future, NPs may also be successful affordable alternative drug-resistant bacterial infections.