A safe and efficient 7‐week immunotherapy protocol with aluminum hydroxide adsorbed vespid venom
نویسندگان
چکیده
منابع مشابه
The safety and efficacy of immunotherapy with aluminum hydroxide-adsorbed venom extract of Vespula spp. An open, retrospective study.
BACKGROUND specific immunotherapy for Hymenoptera Venom (VIT) is considered a life-saving treatment in insect sting allergy. A few studies with depot VIT have been published, but they are mainly focussed on patients sensitized to Apis. METHODS this retrospective study was designed to evaluate both efficacy and safety of depot VIT for Vespula. Thirty-six patients (age range 6-73 years) with a ...
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BACKGROUND Although rapid venom immunotherapy (VIT) protocols have been shown to be safe and effective, this issue has not yet been clarified in Turkey. OBJECTIVE The aim of this study was to evaluate the side effects of rush VIT as well as early clinical and immunological responses in patients with a venom allergy. METHODS Eighteen patients who had a history of severe systemic reactions af...
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New anthrax vaccines currently under development are based on recombinant protective antigen (rPA) and formulated with aluminum adjuvant. Because long-term stability is a desired characteristic of these vaccines, an understanding of the effects of adsorption to aluminum adjuvants on the structure of rPA is important. Using both biophysical and immunological techniques, we compared the structure...
متن کاملA Naturally Occurring Hypoallergenic Variant of Vespid Antigen 5 from Polybia scutellaris Venom as a Candidate for Allergen-Specific Immunotherapy
Stings by insects from the Hymenoptera order are known to cause life-threatening allergic reactions and impair life quality. Despite the effectiveness of conventional vespid venom immunotherapy, more standardized and safer allergy vaccines are required and recombinant hypoallergenic variants are important clinical tools. Antigen 5 is a major allergen of vespid venoms and it was previously repor...
متن کاملComponent-resolved diagnosis in vespid venom-allergic individuals.
BACKGROUND Hymenoptera venom-allergic patients frequently present multiple sensitisations. OBJECTIVES To define the allergic profile by components in wasp allergic patients. To study the usefulness of specific IgE to components in cases of double sensitisation. MATERIALS AND METHODS Wasp allergic patients who needed Polistes and/or Vespula venom immunotherapy were included. Before immunothe...
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ژورنال
عنوان ژورنال: Allergy
سال: 2019
ISSN: 0105-4538,1398-9995
DOI: 10.1111/all.14012