A role for SUMO in nucleotide excision repair
نویسندگان
چکیده
منابع مشابه
SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair
XPC recognizes UV-induced DNA lesions and initiates their removal by nucleotide excision repair (NER). Damage recognition in NER is tightly controlled by ubiquitin and SUMO modifications. Recent studies have shown that the SUMO-targeted ubiquitin ligase RNF111 promotes K63-linked ubiquitylation of SUMOylated XPC after DNA damage. However, the exact regulatory function of these modifications in ...
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ژورنال
عنوان ژورنال: DNA Repair
سال: 2011
ISSN: 1568-7864
DOI: 10.1016/j.dnarep.2011.09.013