A role for inherited metabolic deficits in persistent developmental stuttering
نویسندگان
چکیده
منابع مشابه
Normal interhemispheric inhibition in persistent developmental stuttering.
Imaging studies suggest a right hemispheric (pre)motor overactivity in patients with persistent developmental stuttering (PDS). The interhemispheric inhibition (IHI) studied with transcranial magnetic stimulation is an established measure of the interplay between right and left motor areas. We assessed IHI in 15 young male adults with PDS and 15 age-matched fluent-speaking subjects. We addition...
متن کاملAltered functional connectivity in persistent developmental stuttering
Persistent developmental stuttering (PDS) is a speech disorder that impairs communication skills. Despite extensive research, the core causes of PDS are elusive. Converging evidence from task-induced neuroimaging methods has demonstrated the contributions of the basal ganglia and the cerebellum to PDS, but such task-state neuroimaging findings are often confounded by behavioral performance diff...
متن کاملStuttering as a trait or a state revisited: motor system involvement in persistent developmental stuttering.
Michel Belyk, Shelly Jo Kraft and Steven Brown Department of Psychology, Neuroscience & Behaviour, McMaster University, Hamilton, ON, Canada Department of Neuropsychology & Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Universiteitssingel 40, Maastricht, Limburg 6200 MD, The Netherlands Department of Communication Sciences & Disorders, Wayne State University...
متن کاملSpeechEasy: Altered auditory feedback in Adults with Persistent Developmental Stuttering
The purpose of this proposed study is to assess how one widely-marketed device for the treatment of stuttering (i.e., SpeechEasy) influences stuttering in adults with persistent developmental stuttering (PDS). The first experiment is designed to examine specific parameters (delayed auditory feedback-DAF, frequency altered feedback-FAF settings, Ear Placement-Right versus Left Ear) on ameliorati...
متن کاملAbnormal speech sound representation in persistent developmental stuttering.
OBJECTIVES To determine whether adults with persistent developmental stuttering (PDS) have auditory perceptual deficits. METHODS The authors compared the mismatch negativity (MMN) event-related brain potential elicited to simple tone (frequency and duration) and phonetic contrasts in a sample of PDS subjects with that recorded in a sample of paired fluent control subjects. RESULTS Subjects ...
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ژورنال
عنوان ژورنال: Molecular Genetics and Metabolism
سال: 2012
ISSN: 1096-7192
DOI: 10.1016/j.ymgme.2012.07.020