A review of 76 patients with myelodysplastic syndromes treated with danazol
نویسندگان
چکیده
منابع مشابه
Management of Adult Patients with Myelodysplastic Syndromes
The myelodysplastic syndromes (MDS) form a heterogeneous group of clonal disorders with an increasing incidence in the elderly population and an emerging impact on healthcare resources. MDS are caused by gene mutations affecting the haematopoietic stem cells, leading to ineffective haematopoiesis, characterised by dysplasia and cytopenia, and a propensity to evolve towards secondary acute myelo...
متن کاملInflammatory Arthritis in Patients With Myelodysplastic Syndromes
We describe the characteristics and outcome of inflammatory arthritis in patients with myelodysplastic syndrome (MDS) in a French multicenter retrospective study. Twenty-two patients with MDS (median age, 77.5 yr [interquartile range, 69-81]; 10 women) were included. Inflammatory arthritis presented as polyarthritis in 17 cases (77%) and with symmetric involvement in 15 cases (68%). At diagnosi...
متن کاملEffects of Letrozole Compared with Danazol on Patients with Confirmed Endometriosis: A Randomized Clinical Trial
Background Letrozole is an aromatase inhibitor which can decrease estrogen production in peripheral tissues and endometriosis. Danazol, as an androgen, inhibits estrogen production in ovaries and recently has been introduced as an aromatase inhibitor. This study was designed to compare the effects of Danazol with Letrozole on endometriosis symptom relief. MaterialsAndMethods This study was a ra...
متن کاملA review of anemia as a cardiovascular risk factor in patients with myelodysplastic syndromes.
BACKGROUND Anemia is an important cause of morbidity in MDS patients, principally through increased cardiovascular disease. Transfusion status has been seen to be a significant prognostic factor for disease progression and mortality, yet the relationship between anemia levels and cardiovascular disease is not well understood. OBJECTIVE This study aimed to review the published literature on th...
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ژورنال
عنوان ژورنال: Cancer
سال: 1995
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19950101)75:1<133::aid-cncr2820750124>3.0.co;2-i