A Review Article: Protein Engineering of Therapeutic Enzymes

Through the development of advanced, stimulus-responsive pharmacological systems, protein engineering has potential to alter metabolic drug landscapes. Protein therapies are a fast growing category FDA-approved medications that have improve clinical consequences in long run. therapeutics is still its preliminary phase; however recent advancements skills being used gain direct monitoring over pharmacodynamics. Drugs intended be metabolized under specific conditions known as medicines. create biochemically based smart personalized patient's needs. brings new features and functionality bio-chemical bio-physical modification proteins meet necessities therapeutic applications. Provided enormous capability approaches modify activity bio-catalysts, this review summarizes current studies showing limitations using these methods enzyme engineering. The will concentrate mainly on three types enzymes: Diagnostic enzymes, Fibrinolytic pharmaceutical which restorative agent, prodrug-activating provokes effects, diagnostic remarkable specificity selectivity offer advantages compared conventional analytical techniques.