A retrospective study of 657 women with vaginal intraepithelial neoplasia (VaIN)

Vaginal intraepithelial neoplasia (VaIN) is frequently underdiagnosed. The aim of this study was to explore the clinical characteristics patients with VaIN and identify more sensitive diagnostic methods. This retrospectively analyzed 657 from International Peace Maternal Child Health Hospital during a ten-year period. Among patients, 26.5% were diagnosed 2/3. proportions 2/3 among those who did not undergo hysterectomy 39.5% 24.7%, respectively. sensitivity cytology testing for in only VaIN, concomitant cervical or vulvar lesions, posthysterectomy 56.7%, 66.5%, 72.3%, high-risk human papillomavirus (hrHPV) same categories 87.7%, 86.5%, 74.3%, hrHPV cotesting 95.2%, 95.6%, 95.0%, In 2/3, incidence HPV 16/18 50.6%. However, 1, 22.6 %. severity associated genotyping hysterectomy, but lesions. A combination could increase diagnosis VaIN. 16 18 are most frequent HPV-types Twelve specific subtypes main virus types development 1.