A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
نویسندگان
چکیده
منابع مشابه
A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis.
Intrauterine hypoperfusion/ischemia is one of the major causes of intrauterine/fetal growth restriction, preterm birth, and low birth weight. Most studies of this phenomenon have been performed in either models with severe intrauterine ischemia or models with gradient degree of intrauterine hypoperfusion. No study has been performed in a model on uniform mild intrauterine hypoperfusion (MIUH). ...
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Severe intrauterine ischemia is detrimental to the developing brain. The impact of mild intrauterine hypoperfusion on neurological development, however, is still unclear. We induced mild intrauterine hypoperfusion in rats on embryonic day 17 via arterial stenosis with metal microcoils wrapped around the uterine and ovarian arteries. All pups were born with significantly decreased birth weights....
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In this paper we examine the effect of mild stenosis on blood flow, in an irregular axisymmetric artery with oscillating pressure gradient. The Herschel-Bulkley fluid model has been utilized for this study. The combined influence of an asymmetric shape and surface irregularities of constriction has been explored in this computational study. An extensive quantitative analysis has been performed ...
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The effects of early relief of heavy bilateral carotid stenosis and ischemic postconditioning on hippocampus CA1 neurons are still unclear. In this study, we used a rat model to imitate severe bilateral carotid stenosis in humans. The rats were divided into sham group, carotid stenosis group, stenosis relief group and ischemic postconditioning group. Ischemic postconditioning consisted of three...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2018
ISSN: 1940-087X
DOI: 10.3791/56723