A rare metachronous presentation of periductal stromal sarcoma in a case of recurrent rhabdomyosarcoma – Case report

Periductal stromal sarcoma (PSS) is a an extremely rare low-grade malignant neoplasm arising from breast periductal stroma. It usually occurs in peri and post-menopausal women. Herein, we report case of 14 year girl, known recurrent Rhabdomyosarcoma (RMS) presenting with breast. To the best our knowledge, this first its kind to be reported literature. A 14year Recurrent Pleomorphic retroperitoneum, presented abdominal mass lump right after 10 years. On chemotherapy, regressed progressed size. further evaluation by histopathological examination immunohistochemistry, turned out sarcoma. tumors have histological similarities phyllodes tumors, biphasic presence hypercellular variably atypical, mitotically active stroma hugging benign epithelium. There are very few reports on thus entity. PSS as metachronous presentation RMS even more prevalence multiple soft tissue sarcomas being 0.08%. clinically suspected metastatic lesion, if accessible for biopsy, warrants meticulous ascertain cell origin. The therapeutic strategy prognosis unclear, longer follow up imperative determine clinical outcome. 2 so far younger individuals. 1st RMS.