A rapid HPTLC method to estimate ximenynic acid in semisolid dosage formulation

Semisolid Dosage Forms for Dermatological Application

ceutical dosage forms. They serve as carriers for drugs that are topically delivered by way of the skin, cornea, rectal tissue, nasal mucosa, vagina, buccal tissue, urethral membrane, and external ear lining (1). Because of their peculiar rheological behavior, semisolids can adhere to the application surface for sufficiently long periods before they are washed off. This property helps prolong d...

Validated HPTLC Method for Simultaneous Determination of Quinapril Hydrochloride and Hydrochlorothiazide in a Tablet Dosage Form

Quinapril hydrochloride and hydrochlorothiazide were simultaneously determined by HPTLC in pharmaceutical formulations. The drugs were separated on silica gel 60 F(254) plates using suitable combination of solvents as mobile phase. The validation parameters, tested in accordance with the requirements of ICH guidelines, prove the suitability of methods.

Semisolid Formulation Development: The CRO Approach

A Validated Stability Indicating HPTLC Method for Determination of Cephalexin in Bulk and Pharmaceutical Formulation

A simple, specific, precise and stability-indicating high performance thin layer chromatographic method of analysis of Cephalexin, both as a bulk drug and in formulation was developed and validated. The method employed TLC (Thin Layer Chromatography) aluminum plates pre-coated with silica gel 60 F254 as the stationary phase. The solvent system consisted of Ethyl Acetate : Methanol : Ammonia (6:...

Development and Validation of HPTLC Method for the Estimation of Almotriptan Malate in Tablet Dosage Form

A new, simple, precise and accurate high performance thin layer chromatographic method has been proposed for the determination of almotriptan malate in a tablet dosage form. The drug was separated on aluminum plates precoated with silica gel 60 GF(254) with butanol:acetic acid:water (3:1:1) was used as mobilephase. Quantitative analysis was performed by densitometric scanning at 300 nm. The met...