A Prospective Study of Etiological Agents Among Febrile Patients in Sierra Leone

Undiagnosed Acute Viral Febrile Illnesses, Sierra Leone

Sierra Leone in West Africa is in a Lassa fever-hyperendemic region that also includes Guinea and Liberia. Each year, suspected Lassa fever cases result in submission of ≈500-700 samples to the Kenema Government Hospital Lassa Diagnostic Laboratory in eastern Sierra Leone. Generally only 30%-40% of samples tested are positive for Lassa virus (LASV) antigen and/or LASV-specific IgM; thus, 60%-70...

Implementing an Ebola Vaccine Study - Sierra Leone.

In October 2014, the College of Medicine and Allied Health Sciences of the University of Sierra Leone, the Sierra Leone Ministry of Health and Sanitation, and CDC joined the global effort to accelerate assessment and availability of candidate Ebola vaccines and began planning for the Sierra Leone Trial to Introduce a Vaccine against Ebola (STRIVE). STRIVE was an individually randomized controll...

A Longitudinal Study of Psychosocial Adjustment and Community Reintegration among Former Child Soldiers in Sierra Leone.

Hantavirus in Bat, Sierra Leone

The molecular masses of the PrPres moieties from the 2 cows were also clearly distinct from those from controls with Land H-BSE (Figure). For samples from animals with H-BSE, enzymatic deglycosylation demonstrated PrPres subtypes, 1 and 2, the latter being a C-terminal PrPres fragment of ≈12–14 kDa (6). To investigate whether the novel PrPres type corresponds to PrPres subtype 2, we compared sa...

Paediatrics in Freetown, Sierra Leone.

The Colony of Sierra Leone originated in the sale and cession of a portion of land to Captain John Taylor in 1788 which was placed under the protection of the British Government. The main purpose of the Colony in its inception was to secure a home on the African continent for a number of natives of Africa and some others who, due to various circumstances, had been separated from their countries...