A PROSPECTIVE OBSERVATIONAL STUDY TO COMPARE THE ANTIEMETIC EFFICACY AND SAFETY PROFILE OF TWO COMBINATIONS NAMELY ONDANSETRON-DEXAMETHASONE VERSUS PALONOSETRON-DEXAMETHASONE IN PROPHYLAXIS OF CISPLATIN INDUCED EMESIS
نویسندگان
چکیده
منابع مشابه
New antiemetic drugs.
BACKGROUND Important progress in the prophylaxis of chemotherapy-induced acute and delayed emesis has been achieved but some fundamental needs still remain that requires new, efficacious antiemetic drugs. METHODS A critical review of the results of published studies of aprepitant, a new NK1 receptor antagonist, and of palonosetron, a 5-HT3 receptor antagonist with a longer half-life. RESULT...
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15 صفحه اولa synchronic and diachronic approach to the change route of address terms in the two recent centuries of persian language
terms of address as an important linguistics items provide valuable information about the interlocutors, their relationship and their circumstances. this study was done to investigate the change route of persian address terms in the two recent centuries including three historical periods of qajar, pahlavi and after the islamic revolution. data were extracted from a corpus consisting 24 novels w...
15 صفحه اولDoes dexamethasone enhance control of acute cisplatin induced emesis by ondansetron?
OBJECTIVE To determine the contribution of dexamethasone to the efficacy of the 5-hydroxytryptamine antagonist ondansetron in control of cisplatin induced nausea and vomiting. DESIGN Randomised double blind crossover study. SETTING Two cancer centres in teaching hospitals, one in the United Kingdom and the other in Germany. SUBJECTS 100 patients (53 men and 47 women) new to cisplatin chem...
متن کاملComparative evaluation of triplet antiemetic schedule versus doublet antiemetic schedule in chemotherapy-induced emesis in head and neck cancer patients
PURPOSE To compare the antiemetic combination of palonosetron, dexamethasone, and aprepitant (PDA) with antiemetic combination of ondansetron and dexamethasone (OD) in head and neck cancer patients receiving docetaxel, carboplatin, and 5-FU based chemotherapy. METHODS Sixty previously untreated patients were randomly divided into two groups of thirty patients each. The PDA group received a co...
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ژورنال
عنوان ژورنال: Journal of Evolution of Medical and Dental Sciences
سال: 2016
ISSN: 2278-4748,2278-4802
DOI: 10.14260/jemds/2016/434