A proliferation saturation index to predict radiation response and personalize radiotherapy fractionation

A proliferation saturation index to predict radiation response and personalize radiotherapy fractionation

BACKGROUND Although altered protocols that challenge conventional radiation fractionation have been tested in prospective clinical trials, we still have limited understanding of how to select the most appropriate fractionation schedule for individual patients. Currently, the prescription of definitive radiotherapy is based on the primary site and stage, without regard to patient-specific tumor ...

Use of Apoptotic Biomarkers to Predict Response to Radiotherapy in Breast Cancer Patients

Introduction: To enhance radiation therapy efficiency it is crucial to implement an individual-based treatment. The aim of present study was to identify the mechanism of intrinsic apoptosis pathway on radiosensitivity and normal tissue complications caused by the radiotherapy.   Materials and Methods: radiation-induced apoptosis in periphera...

Cellular response to ionizing radiation: A microRNA story

MicroRNAs (miRNAs) represent a class of small non-coding RNA molecules that regulate gene expression at the post-transcriptional level. They play a crucial role in diverse cellular pathways. Ionizing radiation (IR) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. Recently it has been discovered that mi...

Radiotherapy Dose-Fractionation

constructing a test to predict the translation performance of english translation ma graduates on legal correspondence and deeds as a profession

regarding the ever evolving and improving world on different aspects of knowledge, the need to a worldwide communication would emerge stronger than ever before which calls for special attention on the judgments and best choices for intermediating between the nations. as the language skills for translation are tested separately from translation skills themselves, to assess translation skills pro...