A practice of routine therapeutic drug monitoring for antiepileptics.
نویسندگان
چکیده
منابع مشابه
A Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs
Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practiced ...
متن کاملTherapeutic Drug Monitoring in Pediatric Practice: A Critical Appraisal
The criteria for drug monitoring in children are almost similar as applicable in adults, though certain factors need to be taken into consideration. The dramatic pace of change in other areas of clinical therapeutics has not reflected significantly in the specialty of pediatrics, accounting for the poor development of therapeutic drug monitoring in children. Major drug interactions in the pedia...
متن کاملValidation of a Commercial Assay and Decision Support Tool for Routine Paclitaxel Therapeutic Drug Monitoring (TDM).
BACKGROUND The value of therapeutic drug monitoring (TDM) for paclitaxel (PTX) was recently demonstrated in the largest TDM trial ever conducted in oncology. The trial demonstrated significant reduction in neuropathy when using TDM. Dose adjustment for PTX was based on time above a threshold concentration (Tc>0.05). Tc>0.05 must be calculated with a pharmacokinetic model and complex nonlinear m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Hospital Pharmacy
سال: 1988
ISSN: 2185-9477,0389-9098
DOI: 10.5649/jjphcs1975.14.358