A panorama of mammalian gene expression evolution

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A panorama of mammalian gene expression evolution

Thirty-six years ago, King and Wilson (1975) noticed in their comparison of humans and chimps that the two species, despite having numerous phenotypic differences, are extremely similar in protein sequences. They speculated that changes in gene expression levels and patterns must have played a more important role in phenotypic evolution than changes in protein sequences and functions. However, ...

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ژورنال

عنوان ژورنال: Molecular Systems Biology

سال: 2011

ISSN: 1744-4292,1744-4292

DOI: 10.1038/msb.2011.86