A one-pot multi-component synthesis of novel 2((1H-Indole-3yl) (Phenyl) methyl) malononitrile derivative by utilizing recoverable and efficient TiO2 nanocatalyst

<p>In this research, we have described a facile and user-friendly protocol for the formation of 2((1H-Indole-3yl)(Phenyl)methyl)malononitrile derivatives using recoverable efficient TiO2 nanocatalyst. This is simple incredibly synthesis novel derivatives. Nanoscale used as catalyst. Since TiO<sub>2 </sub>has more surface area easily binds with active site reactive molecule initiates reaction. At last, TiO<sub>2</sub> also recovered it acts multi-component reaction involves indole, malononitrile, aldehyde in presence ethanol solvent The synthetic methodology employed reactions produces substituted 2((1H-Indole-3yl)(Phenyl) methyl) malononitrile an environmentally friendly under modest conditions. study shows that nanocatalyst effective material 2((1H-Indole-3yl) (Phenyl) high yields, rapid at room temperature, effortless product isolation.</p>