منابع مشابه
A Nucleus with Cytoplasmic Features
Intranuclear cytoplasmic structures in cells have been occasionally reported. In most cases, the question has arisen on "pseudoinclusions" (1): i.e., by invagination of the nucleus, portions of the cytoplasm are seemingly enclosed within this structure although they are entirely extranuclear. In such cases, the matter is easily settled by observing that such "nuclear pseudoinclusions" are delim...
متن کاملCytoplasmic dynein: tension generation on microtubules and the nucleus.
Cytoplasmic dynein is a microtubule dependent motor protein that is central to vesicle transport, cell division and organelle positioning. Recent studies suggest that dynein can generate significant pulling forces on intracellular structures as it motors along microtubules. In this review, we discuss how dynein-generated pulling forces position the nucleus and the centrosome.
متن کاملCytoplasmic intermediate filaments mediate actin-driven positioning of the nucleus.
The localization of the nucleus is precisely regulated, and defects in nuclear positioning are observed in diseases such as lissencephaly, cerebellar ataxia and dysplasia. We show here that cytoplasmic intermediate filaments are essential players in actin-dependent positioning of the nucleus. The actin retrograde flow is relayed by a flow of intermediate filaments that accumulate asymmetrically...
متن کاملThe Protoplast: Plasma Membrane, Nucleus, and Cytoplasmic Organelles
Cells represent the smallest structural and functional units of life (Sitte, 1992). Living organisms consist of single cells or of complexes of cells. Cells vary greatly in size, form, structure, and function. Some are measured in micrometers, others in millimeters, and still others in centimeters (fi bers in certain plants). Some cells perform a number of functions; others are specialized in t...
متن کاملKASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus.
Nuclear-cytoskeletal connections are central to fundamental cellular processes, including nuclear positioning and chromosome movements in meiosis. The cytoskeleton is coupled to the nucleoskeleton through conserved KASH-SUN bridges, or LINC complexes, that span the nuclear envelope. KASH proteins localize to the outer nuclear membrane where they connect the nucleus to the cytoskeleton. New find...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1967
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.35.1.266