A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum

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A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum.

Hemojuvelin is a critical regulator of hepcidin expression and can be cleaved by proteases to form soluble hemojuvelin. Soluble hemojuvelin has been recently identified in human serum but the presence and quantity of soluble hemojuvelin in mouse serum is unknown. We developed a two-site enzyme-linked immunosorbent assay using a monoclonal anti-hemojuvelin as the capture antibody and a biotinyla...

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ژورنال

عنوان ژورنال: Haematologica

سال: 2012

ISSN: 0390-6078,1592-8721

DOI: 10.3324/haematol.2012.070136