A Novel Na(I) Coordination Complex with s-Triazine Pincer Ligand: Synthesis, X-ray Structure, Hirshfeld Analysis, and Antimicrobial Activity

The pincer ligand 2,4-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine (bpmt) was used to synthesize the novel [Na(bpmt)2][AuCl4] complex through self-assembly method. In this complex, Na(I) ion is hexa-coordinated with two tridentate N-pincer ligands (bpmt). bpmt units are meridionally coordinated via one short Na-N(s-triazine) and slightly longer Na-N(pyrazole) bonds, resulting in a distorted octahedral geometry around ion. ligand, s-triazine core not found be coplanar pyrazole moieties. Additionally, strongly twisted from another by 64.94°. Based on Hirshfeld investigations, H···H (53.4%) interactions have significant role controlling supramolecular arrangement of complex. addition, Cl···H (12.2%), C···H (11.5%), N···H (9.3%), O···H (4.9%) significant. Antimicrobial investigations revealed that has promising antibacterial antifungal activities. showed enhanced activity for majority studied gram-positive gram-negative bacteria compared free (MIC = 62.5–125 µg/mL vs. MIC 62.5–500 µg/mL, respectively) Amoxicillin > 500 µg/mL) as positive control. had better efficacy 125 against C. albicans µg/mL).