A novel mouse model of obstructive sleep apnea by bulking agent-induced tongue enlargement results in left ventricular contractile dysfunction
نویسندگان
چکیده
منابع مشابه
Subclinical Left Ventricular Dysfunction in Patients with Obstructive Sleep Apnea
OBJECTIVE We aimed to investigate whether fragmented QRS (fQRS) is associated with subclinical left ventricular (LV) dysfunction in patients with obstructive sleep apnea (OSA). SUBJECTS AND METHODS A total of 141 patients with OSA who had normal LV ejection fraction (LVEF) were included in the study. The fQRS was defined as the presence of an additional R wave, notching of R or S wave or the ...
متن کاملA Novel Method for Sensitive Determination of Subclinical Left-Ventricular Systolic Dysfunction in Subjects With Obstructive Sleep Apnea.
BACKGROUND This study was to evaluate the subclinical left-ventricular (LV) systolic dysfunction with 2-dimensional speckle-tracking echocardiography in subjects with obstructive sleep apnea (OSA) with normal left ventricular ejection fraction and without any confounding disease that can cause myocardial dysfunction. METHODS Nineteen healthy individuals and 60 subjects with OSA were included ...
متن کاملLeft ventricular diastolic dysfunction is linked to severity of obstructive sleep apnea Running head: diastole and sleep apnea
Word count: 199) Background Obstructive sleep apnea has been related to increased cardiovascular risk. The present study examined the relationships between respiratory parameters and left ventricular abnormalities in obstructive sleep apnea. Patients/Methods One hundred and fifty newly diagnosed OSA patients without any known cardiovascular disease were included (age = 49±11 years, BMI = 27.1±3...
متن کاملLeft ventricular systolic dysfunction in patients with obstructive sleep apnea syndrome.
STUDY OBJECTIVES Conflicting results have been reported regarding the effects of obstructive sleep apnea syndrome (OSAS) on daytime left ventricular (LV) systolic function. This study aimed to assess the prevalence and causes of LV systolic dysfunction, using radionuclide angiography, in a large group of patients with OSAS. DESIGN AND SETTING A prospective study in the pneumology department o...
متن کاملA novel tongue implant for tongue advancement for obstructive sleep apnea: feasibility, safety and histology in a canine model.
Obstructive sleep apnea (OSA) is a sleep related breathing disorder caused by partial or complete collapse of the upper airway during sleep. The disease is linked with important cardiovascular and cerebrovascular morbidity and mortality. Tongue base collapse is a major cause of upper airway occlusion in OSA and present surgical procedures to prevent this are invasive and inefficient. A novel im...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2020
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0243844