A novel imaging tool; fluorescent organosilica nanoparticles

Helium ion microscopy: a new tool for imaging novel mesoporous silica and organosilica materials.

Helium ion microscopy (HIM) has been used to image mesoporous silica and organosilica for the first time. Images of chiral nematic silica, ethylenesilica, and new benzenesilica reveal the structural organization, pore dimensions and connectivity of these materials on the nanometer length scale.

Cancer optical imaging using fluorescent nanoparticles.

Green fluorescent protein tagging: A novel tool in biomedical research

In recent years, the green fluorescent protein (GFP) isolated from the jellyfish, Aequorea victoria, has become a novel tool in biomedical research. The tagging of GFP to proteins of interest has widely been used in studies involving various biological events both in vitro and in vivo. In this report, the authors demonstrate the utility of GFP tagging for studying localization of protein kinase...

Organosilica nanotubes: large-scale synthesis and encapsulation of metal nanoparticles.

In this communication we have demonstrated the synthesis of organosilica nanotubes with inner diameter of ∼6 nm and their carbonization to form carbon/silica composite nanotubes. Pd nanoparticles. encapsulated in the organosilica and carbon/silica nanotubes show different catalytic activities in the hydrogenation of cyclohexene.

Optical imaging-guided cancer therapy with fluorescent nanoparticles.

The diagnosis and treatment of cancer have been greatly improved with the recent developments in nanotechnology. One of the promising nanoscale tools for cancer diagnosis is fluorescent nanoparticles (NPs), such as organic dye-doped NPs, quantum dots and upconversion NPs that enable highly sensitive optical imaging of cancer at cellular and animal level. Furthermore, the emerging development of...