A novel electrochemical immunosensor for Golgi Protein 73 assay
نویسندگان
چکیده
منابع مشابه
Research on Golgi Protein 73 and Its Corpora Heterogenium
Hepatocellular carcinoma (HCC) is one of the most frequent malignancies, so early diagnosis is crucial to HCC. In recent years, with the rapid development of proteomics and glycomics, new various serum markers related hepatocellular carcinoma were found in succession. Although it is reported that golgi protein 73 (GP73) and its corpora heterogenium (Fucosylated gp73, Fuc-gp73) can be the serum ...
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Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and the third leading cause of cancer-related mortality worldwide. Conflicting results have been reported regarding the use of serum Golgi protein 73 (GP73) as a promising serum marker for the diagnosis of HCC; therefore, the aim of the present study was to provide a systematic review of the diagnostic performance...
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One novel electrochemical immunosensor was constructed by immobilizing capture antibody of alpha-fetoprotein (AFP Ab(1)) on a nafion/nanogold-particle modified glassy carbon electrode. With a sandwich immunoassay, one DNA-derived magnetic nanoprobe, simplified as DNA/(ZMPs-HRP-AFP Ab(2))(n), was employed for the detection of AFP. The fabricated procedure of the proposed biosensor was characteri...
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Please note that technical editing may introduce minor changes to the text and/or graphics, which may alter content. The journal’s standard Terms & Conditions and the Ethical guidelines still apply. In no event shall the Royal Society of Chemistry be held responsible for any errors or omissions in this Accepted Manuscript or any consequences arising from the use of any information it contains. ...
متن کاملSerum Golgi protein 73 is not a suitable diagnostic marker for hepatocellular carcinoma
Golgi protein 73 (GP73) has been suggested as a serum marker for the diagnosis of hepatocellular carcinoma (HCC). However, this has been challenged in recent years. In the present study, we found that the serum GP73 increased in HCC patients with cirrhosis but not in those without cirrhosis. The receiver operating characteristic curve (ROC) analysis demonstrated that serum GP73 had poor perform...
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ژورنال
عنوان ژورنال: Electrochemistry Communications
سال: 2014
ISSN: 1388-2481
DOI: 10.1016/j.elecom.2014.01.021