A novel cationic nanostructured lipid carrier for improvement of ocular bioavailability: Design, optimization, in vitro and in vivo evaluation
نویسندگان
چکیده
منابع مشابه
1. Nanostructured lipid carrier for bioavailability enhancement
Nanostructred lipid carrier(NLC) is second generation drug carrier system having solid matrix at room temperature. This carrier system is made up of physiological, biodegradable and biocompatible lipid materials and surfactants and is accepted by regulatory authorities for application in different drug delivery system. The main objective of this review is to explore the role of NLCs system for ...
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Dorzolamide ophthalmic drop is one of the most common glaucoma medications but it has a short residence time in the eye. The aim of this study is to develop ocular dorzolamide HCl nanoliposomes (DRZ – nanoliposomes) and to evaluate their potential use for the treatment of ocular hypertension. Nanoliposomes were prepared using Reverse-phase evaporation vesicle (REV) and thin layer hydration (TLH...
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Dorzolamide ophthalmic drop is one of the most common glaucoma medications but it has a short residence time in the eye. The aim of this study is to develop ocular dorzolamide HCl nanoliposomes (DRZ – nanoliposomes) and to evaluate their potential use for the treatment of ocular hypertension. Nanoliposomes were prepared using Reverse-phase evaporation vesicle (REV) and thin layer hydration (TLH...
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Rosuvastatin is a lipid lowering agent, which has low solubility and low bioavailability of 20% with oral administration. Therefore the present study was undertaken to improve solubility and bioavailability of Rosuvastatin by formulating it into Nano structured lipid carriers (NLCs) by using stearic acid and Compritol ATO 888 as solid-lipid, Oleic acid as liquid-lipid and Poloxamer 188 as a sur...
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today, information technology and computers are indispensable tools of any profession and translation technologies have become an indispensable part of translator’s workstation. with the increasing demands for high productivity and speed as well as consistency and with the rise of new demands for translation and localization, it is necessary for translators to be familiar with market demands an...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery Science and Technology
سال: 2016
ISSN: 1773-2247
DOI: 10.1016/j.jddst.2016.03.009