A Non-invasive Model for Measuring Nociception after Tooth Pulp Exposure

Cortical stimulation and tooth pulp evoked potentials in rats: a model of direct anti-nociception.

While the effect of cortex stimulation on pain control is widely accepted, its physiological basis remains poorly understood. We chose an animal model of pain to study the influence of sensorimotor cortex stimulation on tooth pulp stimulation evoked potentials (TPEPs). Fifteen awake rats implanted with tooth pulp, cerebral cortex, and digastric muscle electrodes were divided into three groups, ...

The nociceptive withdrawal reflex in conscious dogs: a new, non-invasive model of nociception

A non-invasive method for measuring preimplantation embryo physiology.

The physiology of the early embryo may be indicative of embryo vitality and therefore methods for non-invasively monitoring physiological parameters from embryos could improve preimplantation diagnoses. The self-referencing electrophysiological technique is capable of non-invasive measurement of the physiology of individual cells by monitoring the movement of ions and molecules between the cell...

A Non-Invasive Method for Measuring Contractility in Cardiocytes

We are developing a noninvasive procedure for measuring contractile responses of both adult and neonatal mammalian cardiocytes. This method can be employed to quantify pharmacological effects of drugs on myocytes. Methods for quantifying neonatal cell contraction reported in the literature have required the use of elaborate equipment such as a proximity detector or an atomic force microscope (t...

A Non-invasive Real-Time Method for Measuring Variable Stiffness

The need for adaptability to the environment, energy conservation, and safety during physical interaction with humans of many advanced robotic applications has prompted the development of a number of Variable Stiffness Actuators (VSA). These have been implemented in a variety of ways, using different transduction technologies (electromechanical, pneumatic, hydraulic, but also piezoelectric, act...