A New Synthesis of TE2A—a Potential Bifunctional Chelator for 64Cu
نویسندگان
چکیده
منابع مشابه
New cross-bridged cyclam derivative CB-TE1K1P, an improved bifunctional chelator for copper radionuclides.
A new cross-bridged cyclam chelator, CB-TE1K1P, was developed for copper-based radiopharmaceuticals, and this chelator can be labelled with (64)Cu under mild conditions in high specific activity. DBCO-PEG4-CB-TE1K1P was synthesized for conjugation to proteins, while Dde-CB-TE1K1P((t)Bu2)-OH was synthesized for solid-phase peptide synthesis. Examples of the conjugation chemistry, radiolabelling ...
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ژورنال
عنوان ژورنال: Nuclear Medicine and Molecular Imaging
سال: 2010
ISSN: 1869-3474,1869-3482
DOI: 10.1007/s13139-010-0031-2