A New LC-MS Method for Evaluating the Efficacy of Pesticide Residue Removal from Fruit Surfaces by Washing Agents

Modern agriculture uses pesticides to improve the quality and quantity of crops. However, pesticide residues can remain on agricultural products, posing very serious risks human health life. It is recommended wash fruits vegetables before consumption. To assess removal efficacy residue, a sensitive reliable method based ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was developed optimized for simultaneous determination four (acetamiprid, boscalid, pyraclostrobin, pendimethalin). Isotope-labeled standards were used validate in terms recovery, linearity, matrix effects, precision, sensitivity. The mean recovery values both low-quality control (LQC) high-quality (HQC) transitions range 89–105%, intra-day precision less than 13.7%. limits detection (LOD) quantification (LOQ) 0.003 mg/kg 0.01 mg/kg, respectively. proposed suitable evaluating detergents removing from fruit surfaces.