A new guanine hydrolytic product [4-(or 5-)guanidinoglyoxaline], and its hydrolytic product [4-(or 5-)carbamidoglyoxaline]
نویسندگان
چکیده
منابع مشابه
Pharmacological studies on 4 (or 5)-aminoimidazole-5 (or 4)-carboxamide (AICA) derivatives.
In previous works from our laboratory (1-3) we reported that 4-diazoimidazole-5 carboxamide (diazo-ICA) and 4-(mono or di-substituted) triazenoimidazole-5-carboxamide (mono or dialkyl-TICA) showed marked inhibitory effects on the growth of tumors and bacterial cells. During examination of their toxicity in mice, behavioral sedation caused by these compounds was also observed (2). These observat...
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Ninety per cent of total rat liver hydrolytic activity (1.4 unitslg of fresh tissue) on diadenosine or diguanosine 5’,5”’-P’,P4-tetraphosphate (Ap4A and Gp4G) present in isotonic homogenates sedimented at 37,000 x g. Supernatant activity corresponded to the earlier described, cytosolic and specific, bis(5’-guanosyl) tetraphosphatase or dinucleoside tetraphosphatase (EC 3.6.1.17; Lobaton, C. D.,...
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[reaction: see text] A convertible nucleoside was synthesized and used to prepare the 2'-deoxynucleoside of 5-guanidino-4-nitroimidazole, a putative in vivo product of the reaction of peroxynitrite with guanine. The convertible nucleoside was incorporated into an oligodeoxynucleotide by the phosphoramidite method and converted postsynthetically to yield an oligodeoxynucleotide containing 5-guan...
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(3) first described a syndrome, commonly referred to as "writhing", which was induced in rodents by the intraperitoneal injection of various chemical agents. Collier et al. (4) have recently reported experiments on the abilities of various sub stances, including some occurring in tissues and causing pain in man, to induce abdominal construction in mice. Many investigators have described the non...
متن کاملسنتز دردمای پایین نانوذرات co3o4 از تجزیه گرمایی کمپلکسهای [coiii(nh3)4 or 5(l)](no3)2 or 3 (l=co3, no3, h2o) و شناسایی آنها.
در میان اکسید های فلزات واسطه، تترا اکسید تری کبالت (co3o4) به دلیل داشتن خواص جالب و بی همتا مانند خواص کاتالیستی، مغناطیسی، الکتروکرومیک، خواص نوری و الکتروشیمیایی به طور گسترده ای مورد توجه قرار گرفته است. این اکسید دارای ساختار اسپینل نرمال و یک نیم رسانا از نوع p-با دمای نیل حدود k30 است. روش تجزیه حرارتی پیشماده مولکولی یک روش نوید بخش برای تهیه نانو ساختارهای اکسید فلزات با سطح ویژه زیاد...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1936
ISSN: 0306-3283
DOI: 10.1042/bj0301189