A nano-solution to bone tissue engineering?
نویسندگان
چکیده
منابع مشابه
Bone Tissue Engineering: a Mini-Review
Despite advances in bone tissue engineering, auto grafts from intra-oral or extra-oral donor sites are still the gold standard for treatment of large craniomaxillofacial defects. Biomaterial development, application of growth factor, and stem cells, open new gateway to bone regeneration studies, but real translation from bench to bedside have not yet happened. In this review article, a number o...
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Natural or synthetic hydroxyapatite (HA) has been frequently used as implant materials for orthopaedic and dental applications, showing excellent bioactivity, adequate mechanical rigidity and structure, osteoconductivity and angiogenic properties, no toxicity, and absence of inflammatory or antigenic reactions. HA can be easily synthesized or extracted from natural sources, such as bovine bone....
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BACKGROUND Restoration of craniofacial bone defects has been a concern for oral and maxillofacial surgeons. In this study, the healing effect of fibrin glue scaffold was compared with autologous bone graft in mandibular defects of rabbit. METHODS Bilateral unicortical osteotomy was performed in the diastema region of 10 male Dutch rabbits. The subjects were randomly divided into 2 equal group...
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Bone injuries and defects, caused by trauma, malformation, osteoporosis and tumours, are therapeutically challenging. Autografts and allografts are ideal treatment approaches for bone regeneration. However, they may be associated with a number of complications, and outcomes are variable. Therefore, bone substitute biomaterials, which not only effectively solved the problem of limited supply, bu...
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The aim of this study was to synthetize porous three-dimensional composites, similar with natural bone structure, for using it in tissue engineering. The new composites prepared by freeze-drying of composite gels consist of a mineral phase nanohydroxyapatite and an organic phase type I fibrillar collagen and silk sericin, the latter acting as a glue-like protein that serves as an adhesive, for ...
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ژورنال
عنوان ژورنال: Materials Today
سال: 2015
ISSN: 1369-7021
DOI: 10.1016/j.mattod.2015.09.005