A mini-review on sofosbuvir and daclatasvir treatment in coronavirus disease 2019
نویسندگان
چکیده
منابع مشابه
Understanding the 2019-novel Coronavirus (2019-nCoV) and Coronavirus Disease (COVID-19) Based on Available Evidence - A Review Study
Since December 2019, a new coronavirus, called the 2019-novel coronavirus (2019-nCoV), triggers pneumonia outbreak from Wuhan (Huanan seafood market) across China, which now poses major health threats to public health. The Corona Virus Disease-2019 (COVID-19) epidemic by 2019-nCoV is spreading worldwide, and by March 1, 2020, 67 countries, including Iran, have been affected. According to worldw...
متن کاملA Review of Pharmacotherapy for Coronavirus Disease 2019 (COVID-19)
The epidemic of COVID-19 and its associated acute respiratory syndrome has posed an unprecedented challenge in identifying effective drugs to prevent and treat it. Due to the high prevalence of this disease and the high number of people at risk, medical staff needs accurate evidence regarding effective drug treatments for this infection. There is currently no effective treatment for COVID-19. B...
متن کاملA Review of Coronavirus Disease-2019 (COVID-19)
There is a new public health crises threatening the world with the emergence and spread of 2019 novel coronavirus (2019-nCoV). The virus originated in bats and was transmitted to humans through yet unknown intermediary animals in Wuhan, China in December 2019. The virus spreads faster than its two ancestors the SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), but has lower ...
متن کاملCoronavirus disease 2019 (COVID-19) Immunopathogenesis, Diagnosis, and Treatment
SARS-CoV-2 is a member of the coronaviruses family that causes the outbreak of coronavirus disease 2019 (COVID-19) in China in late 2019 which has exploded to a global pandemic. The reference genome of the SARS-CoV-2 is considered to be very closely related to SARS-CoV and the virus uses the ACE-2 receptor for cellular entry similar to SARS-CoV. The most common symptoms of COVID-19 are fever, c...
متن کاملSofosbuvir and daclatasvir
After entering hepatocytes, the viral genome of the hepatitis C virus (HCV) is translated into a single polypeptide. This polypeptide is subsequently cleaved into viral proteins, including non-structural (NS) proteins NS3, NS4A, NS5B and NS5B RNA dependent RNA polymerase (Figure 1) [3, 4]. These viral proteins are essential for viral replication and assembly making them significant targets for ...
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ژورنال
عنوان ژورنال: New Microbes and New Infections
سال: 2021
ISSN: 2052-2975
DOI: 10.1016/j.nmni.2021.100895