A mathematical model to guide antibiotic treatment strategies

A mathematical model to guide antibiotic treatment strategies

Over the past few decades, the emergence of multidrug resistance (MDR) to antibiotics in bacteria has led to major difficulties in the management of infected patients. At present, there is a serious lack of development of new antibacterial agents. Mathematical models are one approach to understand how antibiotic usage patterns may be optimized. However, the classical approach to modeling the em...

A Guide to Mathematical Quasicrystals

A New Mathematical Model to Investigate Drug Treatment on the Overall Process of Wound Healing

The absence of a universally accepted mathematical model for assessment of the effectiveness of drugs in the process of wound healing is one of the problems the health professionals have been faced. In this study, an “empirical” mathematical model is presented to evaluate its reliability from an experimental viewpoint and from a comparative aspect with previous models used to study wound healin...

A Mathematical Model to Optimize Allocation Sequence in Dispatching Problem

Truck-Shovel fleet, as the most common transportation system in open-pit mines, has a significant part of mining costs, for which optimal management can lead to substantial cost reductions. Among the available dispatch mathematical models, the multi-stage approach is well suited for allocating trucks to respected shovels in a dynamic dispatching program. However, with this kind of modeling sequ...

Sequencing Strategies to Guide Decision Making in Cancer Treatment

In a Perspective, James Topham and Marco Marra discuss progress in the use of genomic information to guide cancer treatment.