A map of protein dynamics during cell-cycle progression and cell-cycle exit
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چکیده
منابع مشابه
A map of protein dynamics during cell-cycle progression and cell-cycle exit
The cell-cycle field has identified the core regulators that drive the cell cycle, but we do not have a clear map of the dynamics of these regulators during cell-cycle progression versus cell-cycle exit. Here we use single-cell time-lapse microscopy of Cyclin-Dependent Kinase 2 (CDK2) activity followed by endpoint immunofluorescence and computational cell synchronization to determine the tempor...
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ژورنال
عنوان ژورنال: PLOS Biology
سال: 2017
ISSN: 1545-7885
DOI: 10.1371/journal.pbio.2003268