A macin identified from Venerupis philippinarum: Investigation on antibacterial activities and action mode
نویسندگان
چکیده
منابع مشابه
Molecular Characterization of a Novel Big Defensin from Clam Venerupis philippinarum
Antimicrobial peptides (AMPs) are important mediators of the primary defense mechanism against microbial invasion. In the present study, a big defensin was identified from Venerupis philippinarum haemocytes (denoted as VpBD) by RACE and EST approaches. The VpBD cDNA contained an open reading frame (ORF) of 285 bp encoding a polypeptide of 94 amino acids. The deduce amino acid sequence of VpBD s...
متن کاملMolecular cloning and characterization of two isoforms of cyclophilin A gene from Venerupis philippinarum.
Cyclophilin A (CypA) is a ubiquitously distributed intracellular protein belonging to the immunophilin family, which is recognized as the cell receptor for the potent immunosuppressive drug cyclosporine A. In the present study, two isoforms of cyclophilin A gene (named as VpCypA1 and VpCypA2) were isolated and characterized from Venerupis philippinarum by RACE approaches. Both VpCypA1 and VpCyp...
متن کاملVibrios isolated from the cultured manila clam (Ruditapes philippinarum): numerical taxonomy and antibacterial activities.
AIMS A numerical taxonomic study of halophilic Vibrio isolated from healthy and brown ring disease (BRD) affected manila clams (Ruditapes philippinarum), harvested from the Atlantic coast of south-western Spain, was performed. METHODS AND RESULTS Characterization of 123 presumptive Vibrio spp. was carried out using 94 phenotypic tests. Simple matching and Jaccard similarity coefficients were ...
متن کاملCloning and characterization of allograft inflammatory factor-1 (AIF-1) from Manila clam Venerupis philippinarum.
Allograft inflammatory factor-1 (AIF-1) is a 17 kDa interferon-γ-inducible Ca(2+)-binding EF-hand protein that plays a significant role not only in different host responses to inflammatory stimuli, but in the whole host immune defense reaction. In the present study, the full-length cDNA of AIF-1 was identified from manila clam Venerupis philippinarum (denoted as VpAIF-1) by cDNA library and RAC...
متن کاملInfluence of intertidal Manila clam Venerupis philippinarum aquaculture on biogeochemical fluxes
Bivalve aquaculture introduces high densities of farmed organisms to the natural environment with potential consequences on a number of ecosystem processes, including modification of nutrient fluxes (e.g. NH4, NOX, PO4, and Si(OH)4) and benthic respiration, and may impact benthic communities. Infaunal clam culture may influence the environment due to the clams themselves [their metabolic proces...
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ژورنال
عنوان ژورنال: Fish & Shellfish Immunology
سال: 2019
ISSN: 1050-4648
DOI: 10.1016/j.fsi.2019.07.031